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Combination with anti-CTLA-4 antibody yields positive results in mouse melanoma
November 8, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
Peregrine Pharmaceuticals will present data at the Society for Immunotherapy of Cancer (SITC) Annual Meeting showing that phosphatidylserine (PS)-targeting antibodies reactivate tumor immunity at multiple levels and that these antibodies, when combined with an anti-CTLA-4 antibody yielded enhanced anti-tumor activity in a preclinical model of melanoma. Peregrine is planning to start a Phase III trial in second-line non-small cell lung cancer (NSCLC) with its lead PS-targeting antibody bavituxima...
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